Home Curriculum Vitae Research Publications Talks Invited International Domestic Links
Talks
Department of Pharmacology
Interdisciplinary Graduate School of Medicine and Engineering
University of Yamanashi
International
2021
[58]Hamada K, Shinozaki Y, Namekata K, Ohno N, Segawa T, Harada T, Kashiwagi K, Koizumi S
Deficiency of P2Y1 receptor induces hypertensive glaucoma-like phenotypes
in mice.
9th World Glaucoma Congress, June 30- July 3, 2021, Virtual Forum
[57] Shinozaki Y, Namekata K, Kashiwagi K, Ohno N, Segawa T, Shigetomi E, Harada T, Koizumi
S
Lack of ABCA1 in astrocytes causes normal tension-glaucoma-like phenotypes
in mice.
9th World Glaucoma Congress, June 30- July 3, 2021, Virtual Forum
[56] Shinozaki Y, Namekata K, Kashiwagi K, Ohno N, Harada T, Koizumi S
Loss of ABCA1 in astrocytes causes normal tension-glaucoma-like optic neuropathy.
ARVO 2021, May 1-7, 2021, Virtual Forum
2020
[55] Y.Shinozaki, K. Namekata, K. Kashiwagi, T. Segawa, N. Ohno, T. Segawa, T. Harada,
K. Kashiwagi, S. Koizumi
Loss of astrocytic ABCA1 induces normal tension glaucoma
FENS 2020, July 11-15, 2020, Virtual Forum
2019
[54] Y.Shinozaki, K. Namekata, K. Kashiwagi, N. Ohno, T. Segawa, T. Harada, S. Koizumi
Deletion of glial ABCA1 causes glaucoma-like optic neuropathy
ISN-ASN 2019, August 4-8, 2019, Montreal, Canada
[53] H. Hoi, T. Horio, E. Shigetomi, Y.Shinozaki, Y. N. Lee, T. Yoshimi, T. Iwata, T. Noda, K. Takahashi, T. Hattori, S.
Koizumi, K, Sawada
Label-free real-time imaging of extracellular lactate from a hippocampal
slice based on charge-transfer-type potentiometric redox sensor arrays.
Transducers 2019, June 23-27, 2019, Berlin, Germany
[52] Y. Ogaeri, C. Kawakami, T. Hizawa, E. Shigetomi, Y.Shinozaki, T. Noda, T. Iwata, K. Takahashi, S. Koizumi, K, Sawada
Hydrogen ion image sensor with barrel-array diffusion suppressor and hippocampal slice imaging.
Transducers 2019, June 23-27, 2019, Berlin, Germany
[51] C. Kawakami, Y. Kee, H, Doi, T. Horio, Y. Kimura, E. Shigetomi, Y.Shinozaki, T. Noda, T. Iwata, K. Takahashi, S. Koizumi, K, Sawada
Hydrogen ion microscope using 2 um pitch pH image sensor and application
for mouse hippocampal slice.
Transducers 2019, June 23-27, 2019, Berlin, Germany
[50] Y.Shinozaki, K. Kashiwagi, K. Namekata, N. Ohno, A. Takeda, T. Harada,
S. Koizumi
Loss-of-function of glial ABCA1 increases the risk for pathogenesis of
glaucoma
9th FAOPS, March 28-31, 2019, Kobe, Hyogo, JAPAN
2018
[49] Y.Shinozaki, K. Kashiwagi, K. Namekata, N. Ohno, A. Takeda, T. Harada, S. Koizumi
Dysfunction of ABCA1 in optic astrocytes causes pathogenesis of glaucoma
Cold Spring Harbor Asia - Novel Insight into Glial Function and Dysfunction, Dec 3-7, 2018, Suzhou, China
[48] Y.Shinozaki, K. Kashiwagi, K. Namekata, N. Ohno, A. Takeda, T. Harada, T. Iwata, S.
Koizumi
Dysregulated P2Y6 receptor signaling increases a risk for pathogenesis of glaucoma
Purines2018, June19-22, Foz Do Iguacu, Brazil
[47] Y.Shinozaki, K. Kashiwagi, K. Namekata, N. Ohno, A. Takeda, T. Harada, T. Iwata, S.
Koizumi
Disordered P2Y6 receptor signaling causes age-dependent pathogenesis ofglaucoma
WCP2018, July 1-6, 2018, Kyoto International Conference Center, Kyoto, Japan
[46] A. Takeda, Y.Shinozaki, K. Kashiwagi, N. Ohno, K. Eto, H. Wake, J. Nabekura, S. Koizumi
Retinal microglia mediate non-cell-autonomous RGC degeneration in glaucoma
model
The 1st International Symposium for Frontend Brain Science of the University
of Yamanashi, Feb 21-22, 2018, Tokyo, Japan
[45] Y.Shinozaki, K. Kashiwagi, K. Namekata, N. Ohno, A. Takeda, T. Harada, T. Iwata, S. Koizumi
Disordered P2 receptor signaling causes ocular hypertension and glaucoma-like
phenotypes
The 1st International Symposium for Frontend Brain Science of the University
of Yamanashi, Feb 21-22, 2018, Tokyo, Japan
2017
[44] Y.J. Choi, Y. Shinozaki et al.
Cell analysis system using a filter-free fluorescence sensor
Transducers 2017, June 18-22, Kaousiung, Taiwan
[43] Y.Shinozaki, K.Kashiwagi, A.Takeda, N.Ohno and S.Koizumi
Dysregulation in purinergic signaling causes hypertensive glaucoma-like
optic neuropathy
ARVO2017, May 7-11, Baltimore, USA
*Travel Grant for ARVO2017 from The Ichiro Kanehara Foundation for the
Promotion of Medical Science & Medical Care
2015
[42] Y. Shinozaki, KF. Tanaka, K. Ikenaka and S. Koizumi
Microglia induce neuroprotective astrocytes via P2Y1 receptor down-regulation
Euroglia2015, July 15-18, Bilbao, Spain
[41] M. Sakai, K. Uchiyama, H. Hori, K. Kobayashi, Y. Shinozaki, K. Shibata, E. Shigetomi and S. Koizumi
Nano-imaging of glia-synapse fine structures responsible for neural functions
APNFO2015, July 7-10, 2015, Hakodate, Japan
[40] M. Sakai, Y. Shinozaki, K. Shibata, E. Shigetomi, S. Koizumi, K. Uchiyama, H. Hori and K. Kobayashi
Nano-imaging for glia-synapse fine structures with a homemade near-field
optical microscope
Optics in the Life Sciences, April 12-15, 2015, Vancouver, Canada
2014
[39] Y.Shinozaki, M. Nomura, K. Iwatsuki, Y. Moriyama, C. Gachet and S. Koizumi
Microglia trigger astrocyte-mediated neuroprotection via purinergic gliotransmission
FENS2014, July 5-9, 2014, Milano, Italy
2013
[38]Y. Shinozaki and S. Koziumi
Purinergic signaling-regulated glial scar foramtion
XI European Meeting on Glial Cells in Health and Diseases (GLIA2013), July
2 - 6, 2013. Berlin, Germany
2012
[37]Y. Shinozaki, Y. Imura, Y. Morizawa, Y. Hirayama, R. Komatsu, K. Shibata, K. Fujishita, E. Shigetomi and S. Koziumi
P2Y1 receptor negatively regulates astrocytic migration and scar-like structure
formation (Oral presentation in Young Investigator Colloquia)
55th Annual Meeting of the Japanese Society for Neurochemistry/ 11th Bennial
meeting of Asian Pacific Society for
Neurochemistry, Sepember 29 - October 2, 2012. Hyogo, Japan
[36] Yoshio Imura, Youichi Shinozaki, Ryohei Komatsu, Yosuke Morizawa, Yuri Hirayama, Keisuke Shibata, Yoshinori
Moriyama,
Schuichi Koizumi
Microglia
Release ATP by a Mechanism of Exocytosis (Poster presentation)
Purine
2012, May 31 ? July 2, 2012, Fukuoka, Japan
[35]
Youichi Shinozaki,
Yoshio Imura, Yosuke Morizawa, Yuri Hirayama, Ryohei Komatsu, Keisuke
Shibata, Kayoko Fujishita and Schuichi Koizumi
Dept.
Neuropharmacol., Interdisciplinary Grad. Sch. Med. and Engineering,
Univ. Yamanashi, JAPAN
P2Y1 receptor blockade enhances astrocytic motility and glial scar formation (Oral presentation)
Purine
2012, May 31 ? July 2, 2012, Fukuoka, Japan
2011
[34]
Keisuke Shibata,
Takeshi Sugawara,
Kayoko Fujishita,
Youichi Shinozaki,
Takashi Matsukawa,
Tsutomu Suzuki
and Schuichi Koizumi
The
astrocyte-targeted therapy by Bushi for the neuropathic pain in mice (Poster presentation)
SfN2011, Washington
D.C. , USA, November 12-16, 2011
[33]Youichi Shinozaki, Koji Sumitomo, Makoto Tsuda, Schuichi Koizumi, Kazuhide
Inoue, and Keiichi Torimitsu
Direct visualization of single receptor structure/dynamics with fast-scanning
atomic force microscopy (Poster presentation)
The 23rd Bennial Meeting of International Society for Neurochemistry (ISN2011),
Athens, Greece. August-1 September, 2011
[32] Koji Sumitomo, Arianna McAllister, Yukihiro Tamba, Youichi Shinozaki,
Keiichi Torimitsu
Analysis of ion channel activities in the lipid bilayer suspended over
microwells on the Si substrate
Biophysical Society 55th Annual Meeting, Baltimore, Maryland, March 5-9,
2011
2010
[31] Youichi Shinozaki, Koji Sumitomo, Makoto Tsuda, Schuichi Koizumi,
Kazuhide Inoue, Keiichi Torimistsu
Direct imaging of P2X4 receptors with fast-scanning atomic force microscopy
The 16th Takeda Science Symposium on Bioscience, Dec. 1-2, 2010, Tokyo,
Japan
[30] Aya Tanaka, Youichi Shinozaki, Koji Sumitomo, Keiichi Torimistu
Visualization of domain dynamics in lipid raft model membranes by high-speed atomic force microscopy
ICSPM18, Dec. 9-11, 2010, Shizuoka, Japan
[29] Youichi Shinozaki, Koji Sumitomo, Keiichi Torimitsu
Ligand-induced conformational changes in N-terminal domain of N-methyl-D-aspartate receptor observed with atomic force microscopy
NC-AFM2010, 4th Aug. 2010. Ishikawa, Japan
2009
[28] Koji Sumitomo, Yukihiro Tamba, Youichi Shinozaki, Keiichi Torimitsu
Formation of liquid ordered domain on Si substrate using giant unilamellar vesicles
ICSPM17, Dec. 10-12, Shizuoka, Japan
[27] Youichi Shinozaki, Koji Sumitomo, Kazuaki Furukawa, Hidetoshi Miyashita,
Yukihiro Tamba, Nahoko Kasai, Hiroshi Nakashima, Keiichi Torimitsu
AFM observation of membrane proteins suspended over nanoscale well
ICSPM17, Dec. 10-12, Shizuoka, Japan
[26] Youichi Shinozaki, Koji Sumitomo, Makoto Tsuda, Schuichi Koizumi, Kazuhide
Inoue, and Keiichi Torimitsu
Direct visualization of single receptor dynamics: the relationship between molecular structure and physiology/pathology
ISNM2009-2, Nov. 4-6, 2009, Aichi, Japan (I won the best poster award!)
[25] N. Kasai, T. Balois, C. S. Ramanujan, Y. Shinozaki, K. Sumitomo, J.
F. Ryan, K. Torimitsu
Examination of reconstitution orientation of AMPA receptors in artificial lipid bilayer
Neuroscience 2009, Oct. 17-21, 2009, Chicago, USA
[24] J. Baranovic, C. S. Ramanujan, N. Kasai, Y. Shinozaki, K. Torimitsu,
J.F. Ryan
AMPA receptors in laterally heterogeneous lipid bilayers (poster)
Neuroscience 2009, Oct. 17-21, 2009, Chicago, USA
[23] Y. Shinozaki, K. Sumitomo, M. Tsuda, S. Koizumi, K. Inoue, and K. Torimitsu
Localization of P2X4 receptors in lipid raft-like structure of in vitro model of cell membrane
Fukuoka Purine 2009, 7/23-7/25, Fukuoka, Japan (I won the best poster award!)
[22] Y. Shinozaki, K. Sumitomo, M. Tsuda, S. Koizumi, K. Inoue, and K.
Torimitsu
Dynamic structural changes in single P2X4 receptors observed with fast-scanning atomic force microscopy
IUPS2009, 7/27-8/1, Kyoto, Japan (poster)
[21] Nahoko Kasai, Chandra Ramanujan, Jelena Baranovic, Youichi Shinozaki,
Akiyoshi Shimada, Koji Sumitomo, John F. Ryan, and Keiichi Torimitsu
Structural observation of a single, reconstituted ionotropic glutamate receptor
IUPS2009, 7/27-8/1, Kyoto, Japan (poster)
[20] Hiroshi Nakashima, Kazuaki Furukawa, Youichi Shinozaki, Koji Sumitomo,
and Keiichi Torimitsu
Molecular-scale detection of antigen-antibody reaction on 2D arrayed gold nanorods
13th IACIS international conference on surface and colloid science and
the 83rd ACS colloid & surface science symposium, June 14-19, 2009,
NY, USA
2008
[19] N. Kasai, C. Rmanujan, Y. Shinozaki, A. Shimada, K. Sumitomo, J. F.
Ryan, K. Torimitsu
Structural change of an ionotropic glutamate receptor reconstituted into lipid bilayer
Neuroscience 2008, Society for Neuroscience, Nov. 15-19, 2008, Washington
DC, USA
[18] Koji Sumitomo, Youichi Shinozaki, Daisuke Takagi, Hiroshi Nakashima,
Yoshihiro Kobayashi, and Keiichi Torimitsu
AFM observation of membrane proteins suspended over CNT network
ICSPM-16, Kanagawa, Japan, 11th December〜13th December,2008
[17] Youichi Shinozaki, Koji Sumitomo and Keiichi Torimitsu
AFM imaging of pore opening/dilation-related structural changes in P2X4 receptors (Oral presentation)
The 4th Workshop of the UK-Japan Bionanotechnology, Hyogo, Japan, 17th
September〜18th September, 2008
[16] Nahoko Kasai, Chandra S. Ramanujan, Youichi Shinozaki, Koji Sumitomo,
John F. Ryan, Keiichi Torimitsu
Reconstitution of ionotropic glutamate receptor and its structure (Oral presentation)
The 4th Workshop of the UK-Japan Bionanotechnology, Hyogo, Japan, 17th
September〜18th September, 2008
[16] Koji Sumitomo, Youichi Shinozaki, Naohoko Kasai, Hiroshi Nalashima,
Ari M. Siitonen, Keiichi Torimitsu, Chandra S. Ramanujan, John F. Ryan
AFM observation of membrane proteins suspended over nanowells: structural and functional analysis (Oral presentation)
The 4th Workshop of the UK-Japan Bionanotechnology, Hyogo, Japan, 17th
September〜18th September, 2008
[15] Youichi Shinozaki, Koji Sumitomo, Makoto Tsuda, Schuichi Koizumi,
Kazuhide Inoue and Keiichi Torimitsu
Single receptor/channel imaging of P2X4 receptor (Oral presentation)
Purines 2008, Copenhagen, Denmark, 29th June〜2nd July, 2008
[14] Keiichi Torimitsu, Youichi Shinozaki and Yuriko Furukawa
Magnesium effect on brain neural development (Poster)
Gordon Research Conference, “Magnesium in biochemical processes & medicine”
CA, USA, 9th〜14th Mar, 2008 (Best poster presentation award)
[13] Nahoko Kasai, Chandra S. Ramanujan, Akiyoshi Shimada, Youichi Shinozaki,
Koji Sumitomo, John F. Ryan, Keiichi Torimitsu
Examination of reconstitution condition for AFM observation of an ionotropic
glutamate receptor (Poster)
Joint meeting of the Biophysical society 52nd annual meeting and 16th international
biophysical congress (IUPAB), CA, USA, 2nd〜6th Feb, 2008 (ポスター発表)
[12] Youichi Shinozaki, Koji Sumitomo and Keiichi Torimitsu
Subunit structures of N-methyl-D-aspartate receptor analyzed by atomic force microscopy (Oral presentation)
Joint meeting of the Biophysical society 52nd annual meeting and 16th international
biophysical congress (IUPAB), CA, USA, 2nd〜6th Feb, 2008 (口頭発表)
2007
[11] Youichi Shinozaki, Ari M. Siitonen, Koji Sumitomo, Kazuaki Furukawa,
Nahoko Kasai and Keiichi Torimitsu
Effect of calcium ion to the lipid vesicle fusion studied by fast-scanning AFM
ICSPM15th , Shizuoka, 6th〜8th Dec, 2007 (口頭発表)
[10] Ari M. Shiitonen, Koji Sumitomo, Chandra S. Ramanujan, Youichi Shinozaki,
Nahoko Kasai, Kazuaki Furukawa, John F. Ryan, and Keiichi Torimitsu
The mechanics analysis of the purple membrane by atomic force microscopy
ACSIN-9th , Tokyo, 11th~15th Nov, 2007 (口頭発表)
[9] Youichi Shinozaki, Koji Sumitomo, Nahoko Kasai, and Keiichi Torimitsu
Direct imaging of ionotropic glutamate receptor proteins using fast-scanning
atomic force microscopy (ポスター発表)
ACSIN-9th , Tokyo, 11th~15th Nov, 2007
[8] Nahoko Kasai, Chandra S. Ramanujan, Youichi Shinozaki, Koji Sumitomo,
John F. Ryan, and Keiichi Torimitsu
Structure observation of a membrane protein reconstituted into an artificial lipid bilayer(口頭発表)
Third workshop of the UK-Japan Bionanotechnology collaboration, Oxford,
UK, 18th〜20th June,2007
[7] Koji Sumitomo, Ari M. Shiitonen, Chandra S. Ramanujan, Youichi Shinozaki,
Nahoko Kasai, Kazuaki Furukawa, John F. Ryan, and Keiichi Torimitsu
Mechanics analysis of the purple membrane suspended over nano-structures (口頭発表)
Third workshop of the UK-Japan Bionanotechnology collaboration, Oxford,
UK, 18th〜20th June,2007
[6] Youichi Shinozaki, Koji Sumitomo and Keiichi Torimitsu
Subunit structures, conformational changes and dynamic observation of purified membrane channel proteins (口頭発表)
Third workshop of the UK-Japan Bionanotechnology collaboration, Oxford,
UK, 18th〜20th June,2007
[5] Nahoko Kasai, Chandra S. Ramanujan, Ichiro Fujimoto, Akiyoshi Shimada,
Youichi Shinozaki, Koji Sumitomo, John F Ryan and Keiichi Torimitsu
Purification, reconstitution and AFM observation of a membrane protein
(ポスター発表)
1st International Symposium of Nanomedicine, Aichi, Japan, 20th〜22nd Apr,
2007
2006
[4] Youichi Shinozaki, Koji Sumitomo and Keiichi Torimitsu
Optimization of protein attachment to the substrate and analysis of conformational
changes in the membrane protein(口頭発表)
ICSPM 14th, Izu Atagawa, Japan, 7th~9th Dec, 2006
[3] Youichi Shinozaki, Koji Sumitomo and Keiichi Torimitsu
High-speed atomic force microscopy of the purified membrane channel protein (口頭発表)
The 2nd workshop of the UK-Japan biotechnology collaboration, Tokyo, Japan,
4th〜6th Dec, 2006
[2] H. Tozaki-Saito, M. Tsuda, K. Inoue, S. Koizumi, Y. Shinozaki, Y. Sato
Upregulation of microglial P2X4 receptors by retinoic acid (ポスター発表)
Neuroscience 2006, Monday, Oct 16, 2006, U.S.A.
2005
2004
[1] Youichi Shinozaki, Schuichi Koizumi, Kazuhide Inoue.
Cytoprotection against oxidative-stress-induced damage of astrocyte. (ポスター発表)
Purines 2004, North Carolina, U.S.A, June, 2004.